Mapping Tumor-Specific Expression QTLs in Impure Tumor Samples
نویسندگان
چکیده
منابع مشابه
Mapping Tumor-Specific Expression QTLs in Impure Tumor Samples
The study of gene expression quantitative trait loci (eQTL) is an effective approach to illuminate the functional roles of genetic variants. Computational methods have been developed for eQTL mapping using gene expression data from microarray or RNA-seq technology. Application of these methods for eQTL mapping in tumor tissues is problematic because tumor tissues are composed of both tumor and ...
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ژورنال
عنوان ژورنال: Journal of the American Statistical Association
سال: 2019
ISSN: 0162-1459,1537-274X
DOI: 10.1080/01621459.2019.1609968